Overview

  • Product nameAnti-Phosphotyrosine antibody [P-TYR-01]
    See all Phosphotyrosine primary antibodies
  • Description
    Mouse monoclonal [P-TYR-01] to Phosphotyrosine
  • SpecificityPhosphotyrosine.
  • Tested applicationsSuitable for: ICC, WBmore details
  • Species reactivity
    Reacts with: Species independent
  • Immunogen

    Phosphotyrosine conjugated to BSA.

  • Positive control
    • Jurkat cells stimulated with anti CD3 antibody (2 min incubation).

Properties

Applications

Our Abpromise guarantee covers the use of ab8076 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC
WB
  • Application notesICC: Use at an assay dependant dilution.
    WB: Use at an assay dependant concentration.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceThe phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine phosphorylated proteins and the biochemical pathways in which they function.

    References for Anti-Phosphotyrosine antibody [P-TYR-01] (ab8076)

    This product has been referenced in:
    • Saxinger C  et al. Fully automated synthesis of (phospho)peptide arrays in microtiter plate wells provides efficient access to protein tyrosine kinase characterization. BMC Immunol 6:1 (2005). Read more (PubMed: 15647109) »
    • Brdicka T  et al. Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation. J Exp Med 191:1591-604 (2000). Read more (PubMed: 10790433) »

    See all 4 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"