Overview

  • Product nameAnti-Phosphotyrosine antibody [PT-66] (Biotin)
    See all Phosphotyrosine primary antibodies
  • Description
    Mouse monoclonal [PT-66] to Phosphotyrosine (Biotin)
  • ConjugationBiotin
  • SpecificityThis antibody reacts specifically with phosphorylated tyrosine, both as free amino acid or conjugated to carriers such as BSA or KLH. No cross-reactivity is observed with non-phosphorylated tyrosine, phosphothreonine, phosphoserine, AMP or ATP.
  • Tested applicationsSuitable for: ELISA, Dot blotmore details
  • Species reactivity
    Reacts with: Species independent
  • Immunogen

    Phosphotyrosine conjugated to BSA

Properties

Applications

Our Abpromise guarantee covers the use of ab49667 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/50000.
Dot blot 1/32000.

Target

  • RelevanceThe phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine phosphorylated proteins and the biochemical pathways in which they function.

References for Anti-Phosphotyrosine antibody [PT-66] (Biotin) (ab49667)

This product has been referenced in:
  • Dvir A  et al. The inhibition of EGF-dependent proliferation of keratinocytes by tyrphostin tyrosine kinase blockers. J Cell Biol 113:857-65 (1991). Read more (PubMed: 1709168) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"