Anti-PI 3 Kinase catalytic subunit gamma antibody (ab70903)

Overview

  • Product name
    Anti-PI 3 Kinase catalytic subunit gamma antibody
    See all PI 3 Kinase catalytic subunit gamma primary antibodies
  • Description
    Rabbit polyclonal to PI 3 Kinase catalytic subunit gamma
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Positive control
    • Skeletal muscle tissue, 293 cell lysates transiently transfected with the PI 3 Kinase catalytic subunit (PI3KCG) gene.

Properties

Applications

Our Abpromise guarantee covers the use of ab70903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Detects a band of approximately 126 kDa (predicted molecular weight: 126 kDa).
ELISA 1/1000.
IHC-P 1/10 - 1/50.

Target

  • Function
    3-phosphorylates the cellular phosphoinositide PtdIns-4,5-biphosphate (PtdIns(4,5)P2) to produce PtdIns-3, 4,5-triiphosphate (PtdIns(3,4,5)P3). Links G-protein coupled receptor activation to the secondary messenger PtdIns(3,4,5)P3 production.
  • Tissue specificity
    Pancreas, skeletal muscle, liver and heart.
  • Pathway
    Phospholipid metabolism; phosphatidylinositol phosphate biosynthesis.
  • Sequence similarities
    Belongs to the PI3/PI4-kinase family.
    Contains 1 PI3K/PI4K domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1 phosphatidylinositol 3 kinase antibody
    • 5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma antibody
    • 5-bisphosphate 3-kinase catalytic subunit gamma isoform antibody
    • p110 gamma antibody
    • p110gamma antibody
    • p120 PI3K antibody
    • p120-PI3K antibody
    • Phosphatidylinositol 3 kinase catalytic 110 kD gamma antibody
    • Phosphatidylinositol 3 kinase gamma, p110 gamma antibody
    • Phosphatidylinositol 3 kinase, catalytic, gamma polypeptide antibody
    • Phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit gamma antibody
    • Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit gamma antibody
    • Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit gamma isoform antibody
    • Phosphatidylinositol-4 antibody
    • Phosphoinositide 3 kinase catalytic gamma polypeptide antibody
    • Phosphoinositide 3 kinase gamma catalytic subunit antibody
    • PI3 kinase p110 subunit gamma antibody
    • PI3-kinase subunit gamma antibody
    • PI3CG antibody
    • PI3K antibody
    • PI3K-gamma antibody
    • PI3Kgamma antibody
    • PIK3 antibody
    • Pik3cg antibody
    • PK3CG_HUMAN antibody
    • PtdIns-3-kinase subunit gamma antibody
    • PtdIns-3-kinase subunit p110-gamma antibody
    • Serine/threonine protein kinase PIK3CG antibody
    see all

Images

  • All lanes : Anti-PI 3 Kinase catalytic subunit gamma antibody (ab70903) at 1/100 dilution

    Lane 1 : Non transfected 293 cell lysate
    Lane 2 : PI 3 Kinase catalytic subunit transfected 293 cell lysate

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 126 kDa
    Observed band size : 126 kDa
    Additional bands at : 140 kDa,55 kDa,72 kDa,90 kDa,95 kDa. We are unsure as to the identity of these extra bands.
  • Formalin-fixed and paraffin-embedded skeletal muscle tissue labelled with ab70903 at 1/10 dilution followed by peroxidase conjugated secondary antibody step and DAB staining.

References

ab70903 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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