The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa).
FunctionCatalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis.
Tissue specificityUbiquitously expressed, with a highest expression in skeletal muscle.
Sequence similaritiesBelongs to the PI3/PI4-kinase family. Contains 1 PI3K/PI4K domain.
Western blot - PI 3 Kinase Class 3 antibody (ab73262)
Anti-PI 3 Kinase Class 3 antibody (ab73262) at 1/1000 dilution + HepG2 whole cell lysates
Predicted band size : 102 kDa Observed band size : 102 kDa
References for Anti-PI 3 Kinase Class 3 antibody (ab73262)
This product has been referenced in:
Lian J et al. A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum. Cell Death Differ18:60-71 (2011).
Read more (PubMed: 20577262) »