Anti-PI 3 Kinase p85 alpha antibody (ab90578)


  • Product nameAnti-PI 3 Kinase p85 alpha antibody
    See all PI 3 Kinase p85 alpha primary antibodies
  • Description
    Mouse monoclonal to PI 3 Kinase p85 alpha
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Recombinant full length Human protein (AAH30815) with a proprietary tag.

  • Positive control
    • Raw 264.7 cell lysate



Our Abpromise guarantee covers the use of ab90578 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 84 kDa.
ELISA Use at an assay dependent dilution.


  • FunctionBinds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
  • Tissue specificityIsoform 2 is expressed in skeletal muscle and brain, and at lower levels in kidney and cardiac muscle. Isoform 2 and isoform 4 are present in skeletal muscle (at protein level).
  • Sequence similaritiesBelongs to the PI3K p85 subunit family.
    Contains 1 Rho-GAP domain.
    Contains 2 SH2 domains.
    Contains 1 SH3 domain.
  • DomainThe SH3 domain mediates the binding to CBLB, and to HIV-1 Nef.
  • Post-translational
    Polyubiquitinated in T-cells by CBLB; which does not promote proteasomal degradation but impairs association with CD28 and CD3Z upon T-cell activation.
    Phosphorylated. Dephosphorylated by PTPRJ.
  • Information by UniProt
  • Database links
  • Alternative names
    • GRB1 antibody
    • p85 alpha antibody
    • p85 antibody
    • P85A_HUMAN antibody
    • Phosphatidylinositol 3 kinase associated p 85 alpha antibody
    • Phosphatidylinositol 3 kinase regulatory 1 antibody
    • Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 1 (p85 alpha) antibody
    • Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha antibody
    • Phosphatidylinositol 3-kinase regulatory subunit alpha antibody
    • Phosphoinositide 3 kinase, regulatory subunit 1 (alpha) antibody
    • PI3 kinase p85 subunit alpha antibody
    • PI3-kinase regulatory subunit alpha antibody
    • PI3-kinase subunit p85-alpha antibody
    • PI3K antibody
    • PI3K regulatory subunit alpha antibody
    • Pik3r1 antibody
    • PtdIns 3 kinase p85 alpha antibody
    • PtdIns-3-kinase regulatory subunit alpha antibody
    • PtdIns-3-kinase regulatory subunit p85-alpha antibody
    see all

Anti-PI 3 Kinase p85 alpha antibody images

  • Anti-PI 3 Kinase p85 alpha antibody (ab90578) at 1 µg/ml + PI 3 Kinase p85 alpha (immunogen) at 0.2 µg

    Predicted band size : 84 kDa
  • Anti-PI 3 Kinase p85 alpha antibody (ab90578) at 1 µg/ml + Raw264.7 cell lysate at 50 µg

    Predicted band size : 84 kDa

References for Anti-PI 3 Kinase p85 alpha antibody (ab90578)

ab90578 has not yet been referenced specifically in any publications.

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