Anti-PI 4 Kinase type 2 beta antibody (ab99143)


  • Product nameAnti-PI 4 Kinase type 2 beta antibody
    See all PI 4 Kinase type 2 beta primary antibodies
  • Description
    Rabbit polyclonal to PI 4 Kinase type 2 beta
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae, Drosophila melanogaster, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 143-192 (IIGVFKPKSE EPYGQLNPKW TKYVHKVCCP CCFGRGCLIP NQGYLSEAGA) of Human PI 4 Kinase type 2 beta (NP_060793).

  • Positive control
    • 721_B cell lysate.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab99143 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 55 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • FunctionTogether with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
  • Tissue specificityWidely expressed.
  • Sequence similaritiesBelongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
    Contains 1 PI3K/PI4K domain.
  • Cellular localizationCytoplasm. Membrane. Mostly cytoplasmic but also found associated with the plasma membrane, the Golgi and endosomes. Compared to PI4K2A, a larger fraction of PI4K2B is cytosolic due to a smaller extent of palmitoylation. Translocates to membranes where it is recruited by PDGF stimulation by a Rac-GTP-dependent mechanism.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2610042N09Rik antibody
    • 4933409G22Rik antibody
    • FLJ11105 antibody
    • P4K2B_HUMAN antibody
    • Phosphatidylinositol 4 kinase type 2 beta antibody
    • Phosphatidylinositol 4 kinase type II beta antibody
    • Phosphatidylinositol 4-kinase type 2-beta antibody
    • Phosphatidylinositol 4-kinase type II-beta antibody
    • PI4K 2 beta antibody
    • PI4K 2b antibody
    • PI4K II beta antibody
    • PI4K IIb antibody
    • Pi4k2b antibody
    • PI4KII-BETA antibody
    • PI4KIIb antibody
    • PIK42B antibody
    • Type II phosphatidylinositol 4 kinase beta isoform antibody
    see all

Anti-PI 4 Kinase type 2 beta antibody images

  • Anti-PI 4 Kinase type 2 beta antibody (ab99143) at 1 µg/ml + 721_B cell lysate at 10 µg

    Predicted band size : 55 kDa

References for Anti-PI 4 Kinase type 2 beta antibody (ab99143)

ab99143 has not yet been referenced specifically in any publications.

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