Overview

  • Product nameAnti-PI4 kinase beta antibody
    See all PI4 kinase beta primary antibodies
  • Description
    Rabbit polyclonal to PI4 kinase beta
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 252-301 (ILSDELKPAH RKRELPSLSP APDTGLSPSK RTHQRSKSDA TASISLSSNL) of Human PI4 kinase beta (NP_002642).

  • Positive control
    • Jurkat cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab94604 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 91 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionPhosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking.
  • Tissue specificityWidely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver.
  • Sequence similaritiesBelongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
    Contains 1 PI3K/PI4K domain.
    Contains 1 PIK helical domain.
  • Cellular localizationEndomembrane system. Mitochondrion outer membrane. Rough endoplasmic reticulum membrane. Golgi apparatus. Cytoplasm, perinuclear region. Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) on the Golgi complex.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp686O1820 antibody
    • FLJ30129 antibody
    • NPIK antibody
    • Phosphatidylinositol 4 kinase beta antibody
    • Phosphatidylinositol 4 kinase catalytic beta antibody
    • Phosphatidylinositol 4 kinase catalytic beta polypeptide antibody
    • Phosphatidylinositol 4 kinase wortmannin sensitive antibody
    • Phosphatidylinositol 4-kinase beta antibody
    • PI4K BETA antibody
    • PI4K-beta antibody
    • PI4K92 antibody
    • PI4KB antibody
    • PI4KB_HUMAN antibody
    • PI4Kbeta antibody
    • PI4KIIIbeta antibody
    • PIK4CB antibody
    • PtdIns 4 kinase antibody
    • PtdIns 4-kinase beta antibody
    • Type III phosphatidylinositol 4 kinase beta antibody
    see all

Anti-PI4 kinase beta antibody images

  • Anti-PI4 kinase beta antibody (ab94604) at 1 µg/ml (in 5% skim milk / PBS buffer) + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 91 kDa

References for Anti-PI4 kinase beta antibody (ab94604)

ab94604 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab94604.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"