Recombinant
RabMAb

Anti-PI4 kinase beta antibody [EPR3758(2)] (ab109418)

Overview

  • Product name
    Anti-PI4 kinase beta antibody [EPR3758(2)]
    See all PI4 kinase beta primary antibodies
  • Description
    Rabbit monoclonal [EPR3758(2)] to PI4 kinase beta
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human PI4 kinase beta.

  • Positive control
    • HeLa, SH-SY5Y, BxPC-3 and Jurkat cell lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab109418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 100 kDa (predicted molecular weight: 91 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function
      Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking.
    • Tissue specificity
      Widely expressed with highest levels in heart, skeletal muscle, pancreas, testis and ovary. Weakly expressed in liver.
    • Sequence similarities
      Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
      Contains 1 PI3K/PI4K domain.
      Contains 1 PIK helical domain.
    • Cellular localization
      Endomembrane system. Mitochondrion outer membrane. Rough endoplasmic reticulum membrane. Golgi apparatus. Cytoplasm, perinuclear region. Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-bisphosphate (PIP2) on the Golgi complex.
    • Information by UniProt
    • Database links
    • Alternative names
      • DKFZp686O1820 antibody
      • FLJ30129 antibody
      • NPIK antibody
      • Phosphatidylinositol 4 kinase beta antibody
      • Phosphatidylinositol 4 kinase catalytic beta antibody
      • Phosphatidylinositol 4 kinase catalytic beta polypeptide antibody
      • Phosphatidylinositol 4 kinase wortmannin sensitive antibody
      • Phosphatidylinositol 4-kinase beta antibody
      • PI4K BETA antibody
      • PI4K-beta antibody
      • PI4K92 antibody
      • PI4KB antibody
      • PI4KB_HUMAN antibody
      • PI4Kbeta antibody
      • PI4KIIIbeta antibody
      • PIK4CB antibody
      • PtdIns 4 kinase antibody
      • PtdIns 4-kinase beta antibody
      • Type III phosphatidylinositol 4 kinase beta antibody
      see all

    Anti-PI4 kinase beta antibody [EPR3758(2)] images

    • All lanes : Anti-PI4 kinase beta antibody [EPR3758(2)] (ab109418) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : SH-SY5Y cell lysate
      Lane 3 : BxPC-3 cell lysate
      Lane 4 : Jurkat cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 91 kDa

    References for Anti-PI4 kinase beta antibody [EPR3758(2)] (ab109418)

    This product has been referenced in:
    • Xiong Y  et al. STAT3-regulated long non-coding RNAs lnc-7SK and lnc-IGF2-AS promote hepatitis C virus replication. Mol Med Rep 12:6738-44 (2015). WB . Read more (PubMed: 26328522) »
    • Téoulé F  et al. The Golgi protein ACBD3, an interactor for poliovirus protein 3A, modulates poliovirus replication. J Virol 87:11031-46 (2013). Read more (PubMed: 23926333) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab109418.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up