Overview

  • Product name
  • Description
    Rabbit polyclonal to PIB5PA
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human PIB5PA (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • Positive control
    • Glomerulus and Renal Tubular Epithelium in Cortex.

Properties

Applications

Our Abpromise guarantee covers the use of ab61147 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 14 µg/ml.

Target

  • Function
    Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles.
  • Sequence similarities
    Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
  • Domain
    The 5 Arg-Ser-Xaa-Ser-Xaa-Xaa (RSXSXX) motifs may constitute binding sites for the 14-3-3 protein.
  • Cellular localization
    Cytoplasm. Predominantly localized to membrane ruffles.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5-bisphosphate 5-phosphatase A antibody
    • Inositol polyphosphate 5-phosphatase antibody
    • Inositol polyphosphate 5-phosphatase J antibody
    • INPP5 antibody
    • Inpp5j antibody
    • Phosphatidylinositol 4 antibody
    • Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A antibody
    • PI5PA_HUMAN antibody
    • PIB5PA antibody
    • PIPP antibody
    see all

Images

  • Ab61147 (14ug/ml) staining human PIB5PA in human glomerulus and renal tubular epithelium in cortex tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue.

References

ab61147 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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