For the best experience on the Abcam website please upgrade to a modern browser such as
Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer Preservative: None
Constituents: 2% Sucrose, PBS
Concentration information loading...
Purity Protein A purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 4 - 8 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Use a concentration of 5 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Function Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly.
Pathway Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.
Involvement in disease Defects in PIGV are the cause of hyperphosphatasia with mental retardation (HPMR) [MIM:239300]. It is a syndrome characterized by elevated serum alkaline phosphatase, severe mental retardation, seizures, hypotonia, facial dysmorphism, and hypoplastic terminal phalanges.
Sequence similarities Belongs to the PIGV family.
Post-translational modifications Not N-glycosylated.
Cellular localization Endoplasmic reticulum membrane.
Information by UniProt
GPI mannosyltransferase 2 antibody
GPI mannosyltransferase II antibody
GPI MT II antibody
Anti-PIGV antibody images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PIGV antibody (ab105697)
Paraffin embedded Human kidney tissue labelled with ab105697 at 8 µg/ml. Positively labelled epithelial cells of the renal tubule are indicated with arrows.
Western blot - PIGV antibody (ab105697)
All lanes : Anti-PIGV antibody (ab105697) at 5 µg/ml Lane 1 : Molecular weight marker Lane 2 : Jurkat cell lysate at 10 µg Predicted band size : 56 kDa
References for Anti-PIGV antibody (ab105697)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"