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Rabbit polyclonal to PIGV
Predicted to work with:
Mouse, Rat, Rabbit, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
Synthetic peptide corresponding to a region within N terminal amino acids 51-100 (FVDQLVEGLL GGLSHWDAEH FLFIAEHGYL YEHNFAFFPG FPLALLVGTE) of Human PIGV (NP_060307)
Jurkat cell lysate, Human kidney tissue
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
Concentration information loading...
Protein A purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 4 - 8 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Use a concentration of 5 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly.
Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.
Involvement in disease
Defects in PIGV are the cause of hyperphosphatasia with mental retardation (HPMR) [MIM:239300]. It is a syndrome characterized by elevated serum alkaline phosphatase, severe mental retardation, seizures, hypotonia, facial dysmorphism, and hypoplastic terminal phalanges.
Belongs to the PIGV family.
Endoplasmic reticulum membrane.
Information by UniProt
GPI mannosyltransferase 2 antibody
GPI mannosyltransferase II antibody
GPI MT II antibody
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PIGV antibody (ab105697)
Paraffin embedded Human kidney tissue labelled with ab105697 at 8 µg/ml. Positively labelled epithelial cells of the renal tubule are indicated with arrows.
Western blot - Anti-PIGV antibody (ab105697)
All lanes : Anti-PIGV antibody (ab105697) at 5 µg/ml Lane 1 : Molecular weight marker Lane 2 : Jurkat cell lysate at 10 µg Predicted band size: 56 kDa Gel concentration: 12%
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"