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Rabbit polyclonal to PIGV - C-terminal
Synthetic peptide within Human PIGV aa 342-371 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
Database link: Q9NUD9
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.09% Sodium azide
Constituent: 99% PBS
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Immunogen affinity purified
ab171510 was purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 55 kDa.
Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly.
Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.
Involvement in disease
Defects in PIGV are the cause of hyperphosphatasia with mental retardation (HPMR) [MIM:239300]. It is a syndrome characterized by elevated serum alkaline phosphatase, severe mental retardation, seizures, hypotonia, facial dysmorphism, and hypoplastic terminal phalanges.
Belongs to the PIGV family.
Endoplasmic reticulum membrane.
Information by UniProt
GPI mannosyltransferase 2 antibody
GPI mannosyltransferase II antibody
GPI MT II antibody
has not yet been referenced specifically in any publications.
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