Overview

  • Product name
    Anti-PIGV antibody - C-terminal
    See all PIGV primary antibodies
  • Description
    Rabbit polyclonal to PIGV - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human PIGV aa 342-371 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q9NUD9

  • Positive control
    • WiDr cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab171510 was purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab171510 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 55 kDa.

Target

  • Function
    Alpha-1,6-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly.
  • Pathway
    Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.
  • Involvement in disease
    Defects in PIGV are the cause of hyperphosphatasia with mental retardation (HPMR) [MIM:239300]. It is a syndrome characterized by elevated serum alkaline phosphatase, severe mental retardation, seizures, hypotonia, facial dysmorphism, and hypoplastic terminal phalanges.
  • Sequence similarities
    Belongs to the PIGV family.
  • Post-translational
    modifications
    Not N-glycosylated.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • GPI mannosyltransferase 2 antibody
    • GPI mannosyltransferase II antibody
    • GPI MT II antibody
    • GPI-MT-II antibody
    • Phosphatidylinositol glycan biosynthesis class V protein antibody
    • Phosphatidylinositol-glycan biosynthesis class V protein antibody
    • PIG-V antibody
    • Pigv antibody
    • PIGV_HUMAN antibody
    see all

Images

  • Anti-PIGV antibody - C-terminal (ab171510) at 1/100 dilution + WiDr cell lysate at 35 µg

    Predicted band size: 55 kDa

References

ab171510 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab171510.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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