Overview

  • Product name
    Anti-PIGZ antibody
  • Description
    Rabbit polyclonal to PIGZ
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human PIGZ aa 276-318.
    Sequence:

    DSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHL


    Database link: Q86VD9

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control
    • Human colon and gallbladder tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab188512 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to some trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is facultative and only scarcely detected, suggesting that it only exists in some tissues.
  • Tissue specificity
    Widely expressed at low level, with highest level in brain and colon.
  • Pathway
    Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.
  • Sequence similarities
    Belongs to the glycosyltransferase 22 family. PIGZ subfamily.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • dol-P-Man dependent GPI mannosyltransferase antibody
      • GPI mannosyltransferase 4 antibody
      • GPI mannosyltransferase IV antibody
      • GPI-MT-IV antibody
      • hSMP3 antibody
      • Phosphatidylinositol glycan anchor biosynthesis class Z antibody
      • phosphatidylinositol glycan, class Z antibody
      • Phosphatidylinositol-glycan biosynthesis class Z protein antibody
      • PIG-Z antibody
      • Pigz antibody
      • PIGZ_HUMAN antibody
      • SMP3 antibody
      • SMP3 homolog antibody
      • SMP3 mannosyltransferase antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PIGZ antibody (ab188512)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PIGZ antibody (ab188512)

      Immunohistochemical analysis of paraffin-embedded Human colon tissue labeling PIGZ with ab188512 at 1/50 dilution.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PIGZ antibody (ab188512)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PIGZ antibody (ab188512)

      Immunohistochemical analysis of paraffin-embedded Human gallbladder tissue labeling PIGZ with ab188512 at 1/50 dilution.

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PIGZ antibody (ab188512)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PIGZ antibody (ab188512)

      Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling PIGZ with ab188512 at 1/50 dilution.

    References

    ab188512 has not yet been referenced specifically in any publications.

    Publishing research using ab188512? Please let us know so that we can cite the reference in this datasheet.

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