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Storage instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage buffer Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4
Concentration information loading...
Purity Protein G purified
Purification notes The antibody was purified from mouse ascitic fluids.
Clone number 3G8
Light chain type kappa
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 18 kDa.
Use at an assay dependent dilution.
Function Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzing pSer/Thr-Pro cis/trans isomerizations.
Sequence similarities Contains 1 PpiC domain. Contains 1 WW domain.
Domain The WW domain is required for the interaction with STIL and KIF20B.
Post-translational modifications Phosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localization Nucleus.
Information by UniProt
DODO, Drosophila, homolog of antibody
Anti-Pin1 antibody [3G8] images
Western blot - Pin1 antibody [3G8] (ab38933)
All lanes : Anti-Pin1 antibody [3G8] (ab38933) at 1/500 dilution Lane 1 : 293T cell lysate Lane 2 : HeLa cell lysate Lane 3 : Jurkat cell lysate Lysates/proteins at 50 µg per lane. Secondary goat anti-mouse secondary antibody conjugated to HRP developed using the ECL technique Predicted band size : 18 kDa Observed band size : 16 kDa ( why is the actual band size different from the predicted?)
References for Anti-Pin1 antibody [3G8] (ab38933)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"