Overview

  • Product name
    Pioglitazone hydrochloride
  • Description
    Selective PPAR-γ agonist
  • Biological description
    Selective PPAR-γ agonist (EC50 values are 280, >1000 and >1000 nM for PPAR isoforms γ, α and δ, respectively). Does not readily cross the blood-brain barrier. Antidiabetic activities in vivo, improves the response to circulating insulin.
  • Purity
    > 99%

Properties

References

This product has been referenced in:
  • Heneka MT  et al. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain 128:1442-53 (2005). Read more (PubMed: 15817521) »
  • Xu HE  et al. Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A 98:13919-24 (2001). Read more (PubMed: 11698662) »
  • Colca JR  et al. Pioglitazone hydrochloride inhibits cholesterol absorption and lowers plasma cholesterol concentrations in cholesterol-fed rats. Diabetes 40:1669-74 (1991). Read more (PubMed: 1756906) »

See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab120794.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

Sign up