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Rabbit polyclonal to PIP5K3
KLH conjugated synthetic peptide selected from the center region of human PIP5K3.
Human breast carcinoma tissue.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.09% Sodium Azide
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Ammonium Sulphate Precipitation
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Predicted molecular weight: 237 kDa.
1/50 - 1/100.
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.
Involvement in disease
Corneal dystrophy, fleck
Contains 1 DEP domain.
Contains 1 FYVE-type zinc finger. Contains 1 PIPK domain.
Endosome membrane. Mainly associated with membranes of the late endocytic pathway.
Information by UniProt
1 phosphatidylinositol 3 phosphate 5 kinase antibody
1 phosphatidylinositol 4 phosphate 5 kinase antibody
1-phosphatidylinositol 3-phosphate 5-kinase antibody
Western blot - Anti-PIP5K3 antibody (ab60207)
All lanes : Anti-PIP5K3 antibody (ab60207) Lane 1 : Non-transfected 293 cell lysate Lane 2 : Transiently transfected 293 cell lysate Lysates/proteins at 2 µg per lane. Predicted band size: 237 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PIP5K3 antibody (ab60207)
Ab60207 (1:50) staining human PIP5K3 in breast carcinoma tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
BC = breast carcinoma.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"