Overview

  • Product nameAnti-PIQ antibody
    See all PIQ primary antibodies
  • Description
    Rabbit polyclonal to PIQ
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 357-406 (LQHYFMGRAL EERAQQHREA LIAQISTNVE QLMKAPSLKE AEGKEPELFL) of Human PIQ (NP_001018865).

  • Positive control
    • Human Fetal Heart Lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab111920 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 54 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Tissue specificityUbiquitously expressed in fetal and adult tissues. Localized to the outer segments and connecting cilia of photoreceptor cells.
  • Involvement in diseaseDefects in IQCB1 are the cause of Senior-Loken syndrome type 5 (SLSN5) [MIM:609254]. SLSN is a renal-retinal disorder, characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease. Typically this disorder becomes apparent during the first year of life.
  • Sequence similaritiesContains 4 IQ domains.
  • Information by UniProt
  • Database links
  • Alternative names
    • IQ calmodulin-binding motif containing 1 antibody
    • IQ calmodulin-binding motif-containing protein 1 antibody
    • IQ motif containing B1 antibody
    • Iqcb1 antibody
    • IQCB1_HUMAN antibody
    • KIAA0036 antibody
    • Nephrocystin-5 antibody
    • NPHP5 antibody
    • p53 and DNA damage-regulated IQ motif protein antibody
    • SLSN5 antibody
    see all

Anti-PIQ antibody images

  • Anti-PIQ antibody (ab111920) at 1 µg/ml + Human Fetal Heart Lysate at 10 µg

    Predicted band size : 54 kDa

References for Anti-PIQ antibody (ab111920)

ab111920 has not yet been referenced specifically in any publications.

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