Overview

  • Product nameAnti-Pirh2 antibody
    See all Pirh2 primary antibodies
  • Description
    Mouse monoclonal to Pirh2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: MAATAREDGA SGQERGQRGC EHYDRGCLLK APCCDKLYTC RLCHDNNEDH QLDRFKVKEV QCINCEKIQH AQQTCEECST LFGEYYCDIC HLFDKDKKQY , corresponding to amino acids 1-101 of Human Pirh2

Properties

Applications

Our Abpromise guarantee covers the use of ab57152 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Contributes to the regulation of CDKN1B and p53/TP53 levels, and thereby contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
    • PathwayProtein modification; protein ubiquitination.
    • Sequence similaritiesContains 1 CHY-type zinc finger.
      Contains 1 CTCHY-type zinc finger.
      Contains 1 RING-type zinc finger.
    • Post-translational
      modifications
      Subject to ubiquitination and proteasomal degradation. Interaction with PLAGL2 or KAT5 enhances protein stability.
    • Cellular localizationNucleus. Nucleus speckle. Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • Androgen receptor N terminal interacting protein antibody
      • Androgen receptor N-terminal-interacting protein antibody
      • ARNIP antibody
      • CH-rich-interacting match with PLAG1 antibody
      • CHIMP antibody
      • E3 ubiquitin-protein ligase Pirh2 antibody
      • hARNIP antibody
      • hPirh2 antibody
      • p53 induced protein with a RING H2 domain antibody
      • p53-induced RING-H2 protein antibody
      • PIRH2E antibody
      • PIRH2F antibody
      • PRO1996 antibody
      • RCHY1 antibody
      • Ring finger and CHY zinc finger domain containing 1 E3 ubiquitin protein ligase antibody
      • RING finger and CHY zinc finger domain-containing protein 1 antibody
      • RING finger protein 199 antibody
      • RNF199 antibody
      • ZCHY antibody
      • ZFP 363 antibody
      • zinc finger CHY type antibody
      • Zinc finger protein 363 antibody
      • ZN363_HUMAN antibody
      • ZNF363 antibody
      see all

    Anti-Pirh2 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57152 Pirh2 antibody at 1ug/ml. Predicted band size of immunogen is 65 kDa

    References for Anti-Pirh2 antibody (ab57152)

    ab57152 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57152.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"