Overview

  • Product nameAnti-PIRT antibody
  • Description
    Rabbit polyclonal to PIRT
  • Tested applicationsSuitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: ETLPKVLEVD EKSPEAKDLL PSQTASSLCI SSRSESVWTT TPRSNWEIYR, corresponding to N terminal amino acids 4-53 of Human PIRT.

  • Positive control
    • Human kidney tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab122783 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

Target

  • FunctionRegulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin. Positively regulates TRPV1 channel activity via phosphatidylinositol-4,5-bisphosphate (PIP2). Binds various phosphoinositide, including phosphatidylinositol-4,5-bisphosphate (PIP2), but not phosphatidylinositol (PI).
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • hCG_1776018 antibody
    • Phosphoinositide interacting regulator of transient receptor potential channels antibody
    • Phosphoinositide-interacting protein antibody
    • Pirt antibody
    • PIRT_HUMAN antibody
    see all

Anti-PIRT antibody images

  • Immunofluorescent staining of Human cell line A-431 shows positivity in plasma membrane and cytoplasm. Recommended concentration of ab122783 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122783, at 1/1000 dilution, staining PIRT in Paraffin Embedded Human kidney tissue by Immunohistochemistry.

References for Anti-PIRT antibody (ab122783)

ab122783 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab122783.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"