Overview

  • Product name
    Pitstop® 1 - negative control
  • Description
    Negative control for clathrin inhibitor Pitstop® 1 (ab120685)
  • Biological description
    Negative control for clathrin inhibitor Pitstop® 1 (ab120685) which is of the same chemical class and has a highly related structure to Pitstop® 1. Inhibits amphiphysin binding to the clathrin TD with an IC50 >100 μM and does not block receptor-mediated endocytosis at concentrations of up to 300 μM (unpublished reports).
  • Purity
    > 98%
  • General notes
    Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Pitstop® is a trademark of Freie Universitat Berlin, Newcastle Innovation Ltd. and Children's Medical Research Institute

Properties

Associated products

References

This product has been referenced in:
  • von Kleist L  et al. Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition. Cell 146:471-84 (2011). Read more (PubMed: 21816279) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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