Overview

  • Product nameAnti-PITX1 antibody
    See all PITX1 primary antibodies
  • Description
    Mouse monoclonal to PITX1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: MPSSMGPGAV PGMPNSGLNN INNLTGSSLN SAMSPGACPY GTPASPYSVY RDTCNSSLAS LRLKSKQHSS FGYGALQGPA SGLNACQYN, corresponding to amino acids 225-314 of Human PITX1

Properties

Applications

Our Abpromise guarantee covers the use of ab55598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.
    • Involvement in diseaseDefects in PITX1 are a cause of congenital clubfoot (CCF) [MIM:119800]; also known as talipes equinovarus (TEV). Clubfoot is a congenital limb deformity defined as fixation of the foot in cavus, adductus, varus, and equinus (i.e. inclined inwards, axially rotated outwards, and pointing downwards) with concomitant soft tissue abnormalities. Clubfoot may occur in isolation or as part of a syndrome. Clubfoot appears to be a multifactorial trait.
    • Sequence similaritiesBelongs to the paired homeobox family. Bicoid subfamily.
      Contains 1 homeobox DNA-binding domain.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • BFT antibody
      • CCF antibody
      • Hindlimb expressed homeobox protein backfoot antibody
      • Hindlimb-expressed homeobox protein backfoot antibody
      • Homeobox protein PITX1 antibody
      • LBNBG antibody
      • Paired like homeodomain 1 antibody
      • Paired like homeodomain transcription factor 1 antibody
      • Paired-like homeodomain transcription factor 1 antibody
      • Pituitary homeo box 1 antibody
      • Pituitary homeobox 1 antibody
      • Pituitary otx related factor antibody
      • Pitx1 antibody
      • PITX1_HUMAN antibody
      • POTX antibody
      • PTX1 antibody
      see all

    Anti-PITX1 antibody images



    • Predicted band size : 34 kDa
      PITX1 antibody (ab55598) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-PITX1 antibody (ab55598)

    ab55598 has not yet been referenced specifically in any publications.

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