Overview

  • Product nameAnti-PITX1 antibody
    See all PITX1 primary antibodies
  • Description
    Rabbit polyclonal to PITX1
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from an internal region of human PITX1.

  • Positive control
    • Extracts from Jurkat cells and COLO cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab72640 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 34 kDa (predicted molecular weight: 34 kDa).
ELISA 1/5000.

Target

  • FunctionMay play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.
  • Involvement in diseaseDefects in PITX1 are a cause of congenital clubfoot (CCF) [MIM:119800]; also known as talipes equinovarus (TEV). Clubfoot is a congenital limb deformity defined as fixation of the foot in cavus, adductus, varus, and equinus (i.e. inclined inwards, axially rotated outwards, and pointing downwards) with concomitant soft tissue abnormalities. Clubfoot may occur in isolation or as part of a syndrome. Clubfoot appears to be a multifactorial trait.
  • Sequence similaritiesBelongs to the paired homeobox family. Bicoid subfamily.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • BFT antibody
    • CCF antibody
    • Hindlimb expressed homeobox protein backfoot antibody
    • Hindlimb-expressed homeobox protein backfoot antibody
    • Homeobox protein PITX1 antibody
    • LBNBG antibody
    • Paired like homeodomain 1 antibody
    • Paired like homeodomain transcription factor 1 antibody
    • Paired-like homeodomain transcription factor 1 antibody
    • Pituitary homeo box 1 antibody
    • Pituitary homeobox 1 antibody
    • Pituitary otx related factor antibody
    • Pitx1 antibody
    • PITX1_HUMAN antibody
    • POTX antibody
    • PTX1 antibody
    see all

Anti-PITX1 antibody images

  • All lanes : Anti-PITX1 antibody (ab72640) at 1/500 dilution

    Lane 1 : extracts from Jurkat cells
    Lane 2 : extracts from COLO cells
    Lane 3 : extracts from Jurkat cells, plus immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 34 kDa
    Observed band size : 34 kDa

References for Anti-PITX1 antibody (ab72640)

ab72640 has not yet been referenced specifically in any publications.

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