Overview

  • Product namePJ34 hydrochloride
  • Description
    Potent, selective PARP-1 inhibitor
  • Biological descriptionPotent, selective PARP-1 inhibitor (EC50 = 20 nM). Able to reduce both cell injury induced following deprivation of oxygen-glucose in vitro and infarct size following focal cerebral ischemia in vivo.
  • Purity> 98%

Properties

    References for PJ34 hydrochloride (ab120981)

    This product has been referenced in:
    • Mazzone GL & Nistri A Effect of the PARP-1 inhibitor PJ 34 on excitotoxic damage evoked by kainate on rat spinal cord organotypic slices. Cell Mol Neurobiol 31:469-78 (2011). Read more (PubMed: 21190076) »
    • Pacher P  et al. Activation of poly(ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure. J Pharmacol Exp Ther 300:862-7 (2002). Read more (PubMed: 11861791) »
    • Stone DH  et al. Effect of PJ34 on spinal cord tissue viability and gene expression in a murine model of thoracic aortic reperfusion injury. Vasc Endovascular Surg 43:444-51 (0). Read more (PubMed: 19640911) »

    See 0 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120981.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"