Anti-PKA beta (catalytic subunit) antibody (ab64801)


  • Product nameAnti-PKA beta (catalytic subunit) antibody
    See all PKA beta (catalytic subunit) primary antibodies
  • Description
    Rabbit polyclonal to PKA beta (catalytic subunit)
  • SpecificityDetects endogenous levels of total PKA beta (catalytic subunit) protein.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    A synthetic peptide derived from an internal region of human PKA beta (catalytic subunit)

  • Positive control
    • Extracts from Jurkat cells and CoLo205 cells



Our Abpromise guarantee covers the use of ab64801 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesELISA: 1/20000.
    WB: 1/500 - 1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 41 kDa). Other bands are detected when using extracts from CoLo205 cells.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux.
    • Tissue specificityIsoform 1 is most abundant in the brain, with low level expression in kidney. Isoform 2 is predominantly expressed in thymus, spleen and kidney. Isoform 3 and isoform 4 are only expressed in the brain.
    • Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
      Contains 1 AGC-kinase C-terminal domain.
      Contains 1 protein kinase domain.
    • Post-translational
      Asn-3 is partially deaminated to Asp giving rise to 2 major isoelectric variants, called CB and CA respectively.
    • Cellular localizationCytoplasm. Nucleus. Translocates into the nucleus (monomeric catalytic subunit) (By similarity). The inactive holoenzyme is found in the cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • cAMP-dependent protein kinase catalytic beta subunit isoform 4ab antibody
      • cAMP-dependent protein kinase catalytic subunit beta antibody
      • KAPCB_HUMAN antibody
      • PKA C beta antibody
      • PKA C-beta antibody
      • PKACB antibody
      • Prkacb antibody
      • protein kinase A catalytic subunit beta antibody
      • Protein kinase cAMP dependent catalytic beta antibody
      see all

    Anti-PKA beta (catalytic subunit) antibody images

    • All lanes : Anti-PKA beta (catalytic subunit) antibody (ab64801) at 1/500 dilution

      Lane 1 : Extracts from Jurkat cells at 5-30ug with no immunizing peptide
      Lane 2 : Extracts from CoLo205 cells at 5-30ug with no immunizing peptide
      Lane 3 : CoLo205 cells at 5-30ug with immunizing peptide at 5-10ug

      Predicted band size : 41 kDa
      Observed band size : 50 kDa (why is the actual band size different from the predicted?)

    References for Anti-PKA beta (catalytic subunit) antibody (ab64801)

    ab64801 has not yet been referenced specifically in any publications.

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