Anti-PKA beta (catalytic subunit) antibody (ab94612)


  • Product nameAnti-PKA beta (catalytic subunit) antibody
    See all PKA beta (catalytic subunit) primary antibodies
  • Description
    Rabbit polyclonal to PKA beta (catalytic subunit)
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Caenorhabditis elegans, Drosophila melanogaster, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within the internal sequence amino acids 288-337 (GVSDIKTHKW FATTDWIAIY QRKVEAPFIP KFRGSGDTSN FDDYEEEDIR) of Human PKA beta (catalytic subunit)(NP_002722).

  • Positive control
    • Human fetal lung lysate



Our Abpromise guarantee covers the use of ab94612 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • FunctionMediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux.
  • Tissue specificityIsoform 1 is most abundant in the brain, with low level expression in kidney. Isoform 2 is predominantly expressed in thymus, spleen and kidney. Isoform 3 and isoform 4 are only expressed in the brain.
  • Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
  • Post-translational
    Asn-3 is partially deaminated to Asp giving rise to 2 major isoelectric variants, called CB and CA respectively.
  • Cellular localizationCytoplasm. Nucleus. Translocates into the nucleus (monomeric catalytic subunit) (By similarity). The inactive holoenzyme is found in the cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • cAMP-dependent protein kinase catalytic beta subunit isoform 4ab antibody
    • cAMP-dependent protein kinase catalytic subunit beta antibody
    • KAPCB_HUMAN antibody
    • PKA C beta antibody
    • PKA C-beta antibody
    • PKACB antibody
    • Prkacb antibody
    • protein kinase A catalytic subunit beta antibody
    • Protein kinase cAMP dependent catalytic beta antibody
    see all

Anti-PKA beta (catalytic subunit) antibody images

  • Anti-PKA beta (catalytic subunit) antibody (ab94612) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal lung lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 41 kDa
  • All lanes : Anti-PKA beta (catalytic subunit) antibody (ab94612) at 1 µg/ml

    Lane 1 : Recombinant human PKA beta (catalytic subunit) protein (ab60837) at 0.1 µg
    Lane 2 : Recombinant human PKA beta (catalytic subunit) protein (ab60837) at 0.01 µg

    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 1 minute

References for Anti-PKA beta (catalytic subunit) antibody (ab94612)

ab94612 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab94612.
Please use the links above to contact us or submit feedback about this product.