Anti-PKA beta (catalytic subunit) (phospho T198) antibody (ab118531)


  • Product name
    Anti-PKA beta (catalytic subunit) (phospho T198) antibody
    See all PKA beta (catalytic subunit) primary antibodies
  • Description
    Rabbit polyclonal to PKA beta (catalytic subunit) (phospho T198)
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Cow, Pig, Caenorhabditis elegans, Drosophila melanogaster
  • Immunogen

    Synthetic phosphopeptide, conjugated to KLH, corresponding to amino acids 193-202 of Human PKA beta (catalytic subunit) with phosphoThr at position 198 (NP_002722.1).

  • Positive control
    • Human Kidney tissue.


Our Abpromise guarantee covers the use of ab118531 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1 - 1/1000.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.


  • Function
    Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux.
  • Tissue specificity
    Isoform 1 is most abundant in the brain, with low level expression in kidney. Isoform 2 is predominantly expressed in thymus, spleen and kidney. Isoform 3 and isoform 4 are only expressed in the brain.
  • Sequence similarities
    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
  • Post-translational
    Asn-3 is partially deaminated to Asp giving rise to 2 major isoelectric variants, called CB and CA respectively.
  • Cellular localization
    Cytoplasm. Nucleus. Translocates into the nucleus (monomeric catalytic subunit) (By similarity). The inactive holoenzyme is found in the cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • cAMP-dependent protein kinase catalytic beta subunit isoform 4ab antibody
    • cAMP-dependent protein kinase catalytic subunit beta antibody
    • KAPCB_HUMAN antibody
    • PKA C beta antibody
    • PKA C-beta antibody
    • PKACB antibody
    • Prkacb antibody
    • protein kinase A catalytic subunit beta antibody
    • Protein kinase cAMP dependent catalytic beta antibody
    see all

Anti-PKA beta (catalytic subunit) (phospho T198) antibody images

  • Human Kidney tissue (formalin-fixed, paraffin-embedded) stained with ab118531 at 5 µg/ml followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-PKA beta (catalytic subunit) (phospho T198) antibody (ab118531)

ab118531 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab118531.
Please use the links above to contact us or submit feedback about this product.


Sign up