Overview

  • Product name
  • Description
    Mouse polyclonal to PKC eta
  • Host species
    Mouse
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Cow, Dog
  • Immunogen

    Full length Human PKC eta (amino acids 1-683; NP_006246.2).

  • Positive control
    • PKC eta transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab167482 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 78 kDa.

Target

  • Function
    This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.
    PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
  • Tissue specificity
    Most abundant in lung, less in heart and skin.
  • Involvement in disease
    Defects in PRKCH may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
  • Sequence similarities
    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 C2 domain.
    Contains 2 phorbol-ester/DAG-type zinc fingers.
    Contains 1 protein kinase domain.
  • Domain
    The C1 domain, containing the phorbol ester/DAG-type region 1 (C1A) and 2 (C1B), is the diacylglycerol sensor and the C2 domain is a non-calcium binding domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • KPCL_HUMAN antibody
    • MGC 5363 antibody
    • MGC26269 antibody
    • MGC5363 antibody
    • nPKC eta antibody
    • nPKC-eta antibody
    • PKC h antibody
    • PKC L antibody
    • PKC-L antibody
    • PKCh antibody
    • PKCL antibody
    • Prkch antibody
    • PRKCL antibody
    • Protein kinase C eta antibody
    • Protein kinase C eta type antibody
    see all

Images

  • All lanes : Anti-PKC eta antibody (ab167482) at 1 µg/ml

    Lane 1 : PKC eta transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Predicted band size: 78 kDa

References

ab167482 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab167482.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up