Overview

  • Product nameAnti-PKC mu antibody [EPR1492(2)]
    See all PKC mu primary antibodies
  • Description
    Rabbit monoclonal [EPR1492(2)] to PKC mu
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human PKC mu.

  • Positive control
    • HeLa, Jurkat, HepG2, and K562 cell lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    A trial size is available to purchase for this antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab108963 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 105 kDa (predicted molecular weight: 102 kDa).
  • Application notesIs unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • FunctionConverts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B.
    • Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
      Contains 1 PH domain.
      Contains 2 phorbol-ester/DAG-type zinc fingers.
      Contains 1 protein kinase domain.
    • Cellular localizationCytoplasm. Membrane. Translocation to the cell membrane is required for kinase activation.
    • Information by UniProt
    • Database links
    • Alternative names
      • KPCD1_HUMAN antibody
      • nPKC D1 antibody
      • nPKC mu antibody
      • nPKC-D1 antibody
      • nPKC-mu antibody
      • nPKCD1 antibody
      • nPKCmu antibody
      • PKC antibody
      • PKC MU antibody
      • PKCM antibody
      • PKCmu antibody
      • PKD 1 antibody
      • PKD antibody
      • PKD1 antibody
      • PRKCM antibody
      • PRKD 1 antibody
      • Prkd1 antibody
      • Protein kinase C mu antibody
      • Protein kinase C mu type antibody
      • Protein kinase D antibody
      • Protein kinase D1 antibody
      • Serine/threonine protein kinase D1 antibody
      • Serine/threonine-protein kinase D1 antibody
      see all

    Anti-PKC mu antibody [EPR1492(2)] images

    • All lanes : Anti-PKC mu antibody [EPR1492(2)] (ab108963) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : Jurkat cell lysate
      Lane 3 : HepG2 cell lysate
      Lane 4 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 102 kDa

    References for Anti-PKC mu antibody [EPR1492(2)] (ab108963)

    This product has been referenced in:
    • Sehgal L  et al. 14-3-3?-Mediated transport of plakoglobin to the cell border is required for the initiation of desmosome assembly in vitro and in vivo. J Cell Sci 127:2174-88 (2014). Mouse, Human . Read more (PubMed: 24610948) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"