Anti-PKM2 antibody (ab38237)

ab38237 has been referenced in 17 publications.

• Abu-Remaileh M  et al. WWOX controls hepatic HIF1a to suppress hepatocyte proliferation and neoplasia. Cell Death Dis 9:511 (2018). PubMed: 29724996
• Liu Y  et al. Clinicopathological and prognostic significance of PKM2 protein expression in cirrhotic hepatocellular carcinoma and non-cirrhotic hepatocellular carcinoma. Sci Rep 7:15294 (2017). IHC-P ; Human . PubMed: 29127353
• Fourcade S  et al. Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance. Aging Cell 16:1404-1413 (2017). WB ; Mouse . PubMed: 28984064
• Wei Y  et al. Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23. Nat Commun 8:14041 (2017). PubMed: 28067230
• Teng Y  et al. MicroRNA-29B (mir-29b) regulates the Warburg effect in ovarian cancer by targeting AKT2 and AKT3. Oncotarget 6:40799-814 (2015). IHC . PubMed: 26512921
• Li W  et al. PKM2 inhibitor shikonin suppresses TPA-induced mitochondrial malfunction and proliferation of skin epidermal JB6 cells. Mol Carcinog 53:403-12 (2014). WB ; Mouse . PubMed: 23255458
• Li W  et al. Sensitizing the therapeutic efficacy of taxol with shikonin in human breast cancer cells. PLoS One 9:e94079 (2014). WB ; Human . PubMed: 24710512
• Hegedus A  et al. HIV-1 pathogenicity and virion production are dependent on the metabolic phenotype of activated CD4+ T cells. Retrovirology 11:98 (2014). WB . PubMed: 25421745
• Morató L  et al. Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy. Brain 136:2432-43 (2013). PubMed: 23794606
• Galino J  et al. Oxidative Damage Compromises Energy Metabolism in the Axonal Degeneration Mouse Model of X-Adrenoleukodystrophy. Antioxid Redox Signal : (2011). WB ; Human, Mouse . PubMed: 21453200
• Wittwer JA  et al. Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells. Cancer Prev Res (Phila) 4:1476-84 (2011). WB ; Human . PubMed: 21673231
• Rafacho A  et al. Glucocorticoids in vivo induce both insulin hypersecretion and enhanced glucose sensitivity of stimulus-secretion coupling in isolated rat islets. Endocrinology 151:85-95 (2010). WB ; Rat . PubMed: 19880808
• Huang SK  et al. LC/MS-based quantitative proteomic analysis of paraffin-embedded archival melanomas reveals potential proteomic biomarkers associated with metastasis. PLoS One 4:e4430 (2009). IHC-P ; Human . PubMed: 19221597
• O'Connell K  et al. Lectin-based proteomic profiling of aged skeletal muscle: decreased pyruvate kinase isozyme M1 exhibits drastically increased levels of N-glycosylation. Eur J Cell Biol 87:793-805 (2008). PubMed: 18602720
• Doran P  et al. Opposite pathobiochemical fate of pyruvate kinase and adenylate kinase in aged rat skeletal muscle as revealed by proteomic DIGE analysis. Proteomics 8:364-77 (2008). PubMed: 18050275
• Christofk HR  et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 452:230-3 (2008). WB ; Human . PubMed: 18337823
• Christofk HR  et al. Pyruvate kinase M2 is a phosphotyrosine-binding protein. Nature 452:181-6 (2008). WB ; Human . PubMed: 18337815