The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Detects a band of approximately 99 kDa (predicted molecular weight: 99 kDa).
FunctionContributes to invasiveness in malignant prostate cancer.
Tissue specificityExpressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.
Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. Contains 1 AGC-kinase C-terminal domain. Contains 1 protein kinase domain. Contains 3 REM (Hr1) repeats.
DomainThe C1 domain does not bind the diacylglycerol (DAG).