Overview

  • Product nameAnti-PLA1A antibody
    See all PLA1A primary antibodies
  • Description
    Rabbit polyclonal to PLA1A
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 336-366 of Human PLA1A.

  • Positive control
    • CEM cell line and Mouse liver tissue lysates.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab104003 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 50 kDa.

Target

  • FunctionHydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.
  • Tissue specificityWidely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney.
  • Sequence similaritiesBelongs to the AB hydrolase superfamily. Lipase family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • AA986889 antibody
    • NMD antibody
    • OTTHUMP00000215248 antibody
    • OTTHUMP00000215249 antibody
    • OTTHUMP00000215250 antibody
    • Phosphatidylserine specific phospholipase A1 antibody
    • Phosphatidylserine specific phospholipase A1alpha antibody
    • Phosphatidylserine-specific phospholipase A1 antibody
    • Phospholipase A1 member A antibody
    • pla1a antibody
    • PLA1A_HUMAN antibody
    • PS PLA1 antibody
    • PS-PLA1 antibody
    • PSPLA 1 antibody
    • PSPLA1 antibody
    see all

Anti-PLA1A antibody images

  • Anti-PLA1A antibody (ab104003) at 1/100 dilution + CEM cell line lysates at 35 µg

    Predicted band size : 50 kDa
  • Anti-PLA1A antibody (ab104003) at 1/100 dilution + Mouse liver tissue lysates at 35 µg

    Predicted band size : 50 kDa

References for Anti-PLA1A antibody (ab104003)

ab104003 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"