Overview

  • Product name
  • Description
    Rabbit polyclonal to PLA1A
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 336-366 of Human PLA1A.

  • Positive control
    • CEM cell line and Mouse liver tissue lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab104003 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 50 kDa.

Target

  • Function
    Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.
  • Tissue specificity
    Widely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney.
  • Sequence similarities
    Belongs to the AB hydrolase superfamily. Lipase family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • AA986889 antibody
    • NMD antibody
    • OTTHUMP00000215248 antibody
    • OTTHUMP00000215249 antibody
    • OTTHUMP00000215250 antibody
    • Phosphatidylserine specific phospholipase A1 antibody
    • Phosphatidylserine specific phospholipase A1alpha antibody
    • Phosphatidylserine-specific phospholipase A1 antibody
    • Phospholipase A1 member A antibody
    • pla1a antibody
    • PLA1A_HUMAN antibody
    • PS PLA1 antibody
    • PS-PLA1 antibody
    • PSPLA 1 antibody
    • PSPLA1 antibody
    see all

Images

  • Anti-PLA1A antibody (ab104003) at 1/100 dilution + CEM cell line lysates at 35 µg

    Predicted band size : 50 kDa
  • Anti-PLA1A antibody (ab104003) at 1/100 dilution + Mouse liver tissue lysates at 35 µg

    Predicted band size : 50 kDa

References

ab104003 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab104003.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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