Anti-PLAC8 antibody (ab122652)
Key features and details
- Rabbit polyclonal to PLAC8
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-PLAC8 antibody
See all PLAC8 primary antibodies -
Description
Rabbit polyclonal to PLAC8 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
antigen, corresponding to amino acids 1-115 of Human PLAC8. (Q9NZF1)
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Positive control
- Human tonsil tissue. RT-4 cell lysate. Human liver and tonsil tissue lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab122652 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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WB |
Use a concentration of 0.04 - 0.4 µg/ml.
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Notes |
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IHC-P
1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
WB
Use a concentration of 0.04 - 0.4 µg/ml. |
Target
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Tissue specificity
Expressed at high levels in plasmacytoid dendritic cells. High expression in spleen, lymph nodes, peripheral blood leukocytes, and bone marrow, with lower expression in thymus, appendix, and fetal liver. -
Sequence similarities
Belongs to the cornifelin family. - Information by UniProt
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Database links
- Entrez Gene: 51316 Human
- Omim: 607515 Human
- SwissProt: Q9NZF1 Human
- Unigene: 546392 Human
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Alternative names
- C15 antibody
- Onzin antibody
- PLAC8 antibody
see all
Images
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ab122652 at 1/200 dilution staining PLAC8 in paraffin-embedded Human tonsil tissue by Immunohistochemistry.
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All lanes : Anti-PLAC8 antibody (ab122652) at 1/250 dilution
Lane 1 : RT-4 cell lysate
Lane 2 : U-251 MG cell lysate
Lane 3 : Human plasma lysate
Lane 4 : Human liver tissue lysate
Lane 5 : Human tonsil tissue lysate
Developed using the ECL technique.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab122652 has been referenced in 5 publications.
- Barragán-Zúñiga LJ et al. Evaluation of the PLAC8 Gene in Mexican Women With and Without Preeclampsia and Obesity. Front Med (Lausanne) 9:795309 (2022). PubMed: 35252239
- Chen W et al. PLAC8 Overexpression Promotes Lung Cancer Cell Growth via Wnt/β-Catenin Signaling. J Immunol Res 2022:8854196 (2022). PubMed: 35497881
- Hung CS et al. Expression pattern of placenta specific 8 and keratin 20 in different types of gastrointestinal cancer. Mol Med Rep 21:659-666 (2020). PubMed: 31974611
- Huang CC et al. Gut butyrate-producing organisms correlate to Placenta Specific 8 protein: Importance to colorectal cancer progression. J Adv Res 22:7-20 (2020). PubMed: 31956438
- Blue EK et al. Epigenetic Regulation of Placenta-Specific 8 Contributes to Altered Function of Endothelial Colony-Forming Cells Exposed to Intrauterine Gestational Diabetes Mellitus. Diabetes 64:2664-75 (2015). PubMed: 25720387