Anti-Placental Protein 14 / Glycodelin A antibody (ab17247)

Overview

  • Product nameAnti-Placental Protein 14 / Glycodelin A antibody
    See all Placental Protein 14 / Glycodelin A primary antibodies
  • Description
    Mouse monoclonal to Placental Protein 14 / Glycodelin A
  • Tested applicationsSuitable for: IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native human placental protein 14 (glycodelin A) purified from second trimester amniotic fluid.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 15mM Sodium Azide
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab17247 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ELISA 1/7000.

Target

  • FunctionThis protein is, quantitatively, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy.
  • Sequence similaritiesBelongs to the calycin superfamily. Lipocalin family.
  • Post-translational
    modifications
    At least two differentially glycosylated forms are found. Glycodelin-A (GdA) (amniotic fluid) with contraceptive and immunosuppressive activities and glycodelin-S (Gds) (seminal plasma) whose role is not yet known. The gender-specific glycosylation may serve to regulate key process involved in human reproduction.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Alpha uterine protein antibody
    • gD antibody
    • GdA antibody
    • GdF antibody
    • GdS antibody
    • Glycodelin A antibody
    • Glycodelin antibody
    • Glycodelin F antibody
    • Glycodelin S antibody
    • MGC138509 antibody
    • MGC142288 antibody
    • PAEG antibody
    • PAEP antibody
    • PAEP_HUMAN antibody
    • PEG antibody
    • PEP antibody
    • Placental protein 14 antibody
    • PP14 antibody
    • Pregnancy-associated endometrial alpha-2 globulin antibody
    • Progestagen-associated endometrial protein antibody
    • Progesterone-associated endometrial protein antibody
    see all

Anti-Placental Protein 14 / Glycodelin A antibody images

  • ab17247 staining endometrial tissue from the late secretory phase.  Staining is restricted to the glandular cells.

References for Anti-Placental Protein 14 / Glycodelin A antibody (ab17247)

This product has been referenced in:
  • Wang P  et al. The Role of Placental Protein 14 in the Pathogenesis of Endometriosis. Reprod Sci N/A:N/A (2013). IHC ; Human . Read more (PubMed: 23670949) »
  • Leach RE  et al. High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples. Hum Reprod 27:814-828 (2012). IHC-P ; Human . Read more (PubMed: 22215622) »

See all 4 Publications for this product

Product Wall

Thank you for contacting us.

Yes, in addition to the primary antibody, only a secondary antibody is needed.

I can recommend a couple secondariesthat are HRP-conjugated:

http://www.abcam.com/Donkey-polyclonal-Secondary-Ant...

Read More

Thank you for contacting us.

This antibody ab17247 has so far only been tested in indirect ELISA (coating the sample to the plate, and then using primary and secondary antibodies). It has not been tried in sandwich ELISA, thus, we do not hav...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"