Overview

  • Product nameAnti-Plakophilin 2 antibody
    See all Plakophilin 2 primary antibodies
  • Description
    Goat polyclonal to Plakophilin 2
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Rat
    Predicted to work with: Horse, Cow, Dog, Human
  • Immunogen

    Synthetic peptide:

    C-RGTAQYSSQKSVEER

    , corresponding to internal sequence amino acids 125-139 of Human Plakophilin 2 (NP_001005242.2)

  • Positive control
    • Mouse heart lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab113491 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 88 kDa).
ELISA 1/16000.

Target

  • FunctionMay play a role in junctional plaques.
  • Tissue specificityDetected in heart right ventricle (at protein level). Widely expressed. Found at desmosomal plaques in simple and stratified epithelia and in non-epithelial tissues such as myocardium and lymph node follicles. In most stratified epithelia found in the desmosomes of the basal cell layer and seems to be absent from suprabasal strata.
  • Involvement in diseaseFamilial arrhythmogenic right ventricular dysplasia 9
  • Sequence similaritiesBelongs to the beta-catenin family.
    Contains 8 ARM repeats.
  • Cellular localizationNucleus. Cell junction > desmosome. Nuclear and associated with desmosomes.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARVD 9 antibody
    • ARVD9 antibody
    • PKP 2 antibody
    • PKP2 antibody
    • PKP2_HUMAN antibody
    • Plakophilin-2 antibody
    • Plakophilin2 antibody
    see all

Anti-Plakophilin 2 antibody images

References for Anti-Plakophilin 2 antibody (ab113491)

ab113491 has not yet been referenced specifically in any publications.

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