Overview

  • Product name
    Anti-Plakophilin 2 antibody
    See all Plakophilin 2 primary antibodies
  • Description
    Rabbit polyclonal to Plakophilin 2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Horse, Cat
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 143 - 192 (HPLRRLEISP DSSPERAHYT HSDYQYSQRS QAGHTLHHQE SRRAALLVPP) of Human Plakophilin 2 (NP_001005242).

  • Positive control
    • COLO205 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab98328 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 93 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    May play a role in junctional plaques.
  • Tissue specificity
    Detected in heart right ventricle (at protein level). Widely expressed. Found at desmosomal plaques in simple and stratified epithelia and in non-epithelial tissues such as myocardium and lymph node follicles. In most stratified epithelia found in the desmosomes of the basal cell layer and seems to be absent from suprabasal strata.
  • Involvement in disease
    Familial arrhythmogenic right ventricular dysplasia 9
  • Sequence similarities
    Belongs to the beta-catenin family.
    Contains 8 ARM repeats.
  • Cellular localization
    Nucleus. Cell junction > desmosome. Nuclear and associated with desmosomes.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARVD 9 antibody
    • ARVD9 antibody
    • PKP 2 antibody
    • PKP2 antibody
    • PKP2_HUMAN antibody
    • Plakophilin-2 antibody
    • Plakophilin2 antibody
    see all

Images

  • Anti-Plakophilin 2 antibody (ab98328) at 1 µg/ml (in 5% skim milk / PBS buffer) + COLO205 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 93 kDa

References

ab98328 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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