Anti-Plakophilin 3 antibody [E612B11F8] (ab33070)

Overview

  • Product name
    Anti-Plakophilin 3 antibody [E612B11F8]
    See all Plakophilin 3 primary antibodies
  • Description
    Mouse monoclonal [E612B11F8] to Plakophilin 3
  • Tested applications
    Suitable for: WB, ICC, IHC-Fr, IPmore details
  • Species reactivity
    Reacts with: Mouse, Dog, Human, Pig, Xenopus laevis
  • Immunogen

    Synthetic peptide:

    CKLHRDFAKGYRKED

    conjugated to KLH via an additional cysteine residue at the N terminus, corresponding to amino acids 779/793 of Human Plakophilin 3

  • Epitope
    ab33070 reacts with an epitope located between residues 779/793 in plakophilin 3.

Properties

Applications

Our Abpromise guarantee covers the use of ab33070 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ICC
IHC-Fr
IP
  • Application notes
    ICC: Use at an assay dependent dilution.
    Note: cells need to be methanol fixed.
    IHC-Fr: 1/25 - 1/200, using avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent.
    Note: For optimal results, fixed cells or tissues should be treated with 0.2% Triton-X 100 for 5 min. prior to incubation with primary antibody.
    IP: Use at an assay dependent dilution.
    WB: 1/100 - 1/1000. Predicted molecular weight: 87 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      May play a role in junctional plaques.
    • Tissue specificity
      Found in desmosomes of most simple and stratified epithelia. Not found in foreskin fibroblasts and various sarcoma-derived cell lines. Beside dendritic reticular cells of lymphatic follicles not found in non-epithelial desmosome-bearing tissues.
    • Sequence similarities
      Belongs to the beta-catenin family.
      Contains 8 ARM repeats.
    • Cellular localization
      Nucleus. Cell junction > desmosome. Nuclear and associated with desmosomes.
    • Information by UniProt
    • Database links
    • Alternative names
      • PKP 3 antibody
      • PKP3 antibody
      • PKP3_HUMAN antibody
      • Plakophilin 3b antibody
      • Plakophilin-3 antibody
      • Plakophilin3 antibody
      see all

    References for Anti-Plakophilin 3 antibody [E612B11F8] (ab33070)

    ab33070 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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