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ab112238 induces mouse platelet aggregation in the absence of plasma components via an FcR-independent mechanism. A dramatic increase in tyrosine phosphorylation of the 52 kDa Shc protein was observed during AIP21-mediated platelet aggregation.
Our Abpromise guarantee covers the use of ab112238 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Functional Studies||Use at an assay dependent concentration.|
|Flow Cyt||Use 1µg for 106 cells. ab35768-Rat monoclonal IgM, is suitable for use as an isotype control with this antibody.|