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Storage instructions Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
Storage buffer Preservative: 0.09% Sodium azide Constituent: 99% PBS
Concentration information loading...
Purity Immunogen affinity purified
Purification notes ab123668 is purified through a protein A column, followed by peptide affinity purification.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 89 kDa.
Function Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow.
Tissue specificity Present in corneal epithelial cells (at protein level).
Sequence similarities Contains 1 C2 domain. Contains 3 EF-hand domains. Contains 1 PH domain. Contains 1 PI-PLC X-box domain. Contains 1 PI-PLC Y-box domain.
Domain The C2 domain is a Ca(2+)-dependent membrane-targeting module. The PH domain mediates interaction with the surface membrane by binding to PIP2.
Cellular localization Membrane. Cytoplasm. Cleavage furrow. Localizes at the cleavage furrow during cytokinesis.
Information by UniProt
5-bisphosphate phosphodiesterase delta-3 antibody
Phosphoinositide phospholipase C-delta-3 antibody
Anti-PLC-delta-3 antibody images
References for Anti-PLC-delta-3 antibody (ab123668)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"