The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 100 kDa (predicted molecular weight: 148 kDa).
1/50 - 1/100.
FunctionThe production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Post-translational modificationsPhosphorylated on tyrosine residues; upon ligand-induced activation of a variety of growth factor receptors and immune system receptors. Increases phospholipase activity.
ab63493, used at a dilution of 1/50, staining PCLG 2 by immunohistochemistry analysis of paraffin-embedded
human breast carcinoma tissue in the absence (left) and presence (right) of the blocking peptide
References for Anti-PLCG 2 antibody (ab63493)
has not yet been referenced specifically in any publications.
Publishing research using ab63493? Please let us know so that we can cite the reference in this datasheet.
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