Overview

  • Product nameAnti-PLCL1 antibody
    See all PLCL1 primary antibodies
  • Description
    Rabbit polyclonal to PLCL1
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A KLH conjugated synthetic peptide selected from the N terminal region of Human PLCL1 (NP_006217.2)

  • Positive control
    • Jurkat cell line lysates

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesThis antibody is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab93425 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 123 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInvolved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C.
    • Tissue specificityExpressed in a variety of fetal and adult organs including brain, lung and kidney. Its expression was greatly reduced in small and non-small cell lung carcinoma. Isoform 1 is predominantly expressed in brain.
    • Sequence similaritiesContains 1 C2 domain.
      Contains 1 PH domain.
      Contains 1 PI-PLC X-box domain.
      Contains 1 PI-PLC Y-box domain.
    • Post-translational
      modifications
      Phosphorylated by the catalytic subunit of PKA. Phosphorylation of Thr-93 resulted in dissociation of PPP1C from PRIP1.
    • Cellular localizationCytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • Inactive phospholipase C-like protein 1 antibody
      • Inactive protein 1 antibody
      • Phospholipase C deleted in lung carcinoma antibody
      • Phospholipase C epsilon antibody
      • Phospholipase C like 1 antibody
      • Phospholipase C related but catalytically inactive protein antibody
      • Phospholipase C related, but catalytically inactive protein antibody
      • Phospholipase C-deleted in lung carcinoma antibody
      • Phospholipase C-related but catalytically inactive protein antibody
      • Phospholipase C-related catalytically antibody
      • PLC-L1 antibody
      • PLCE antibody
      • PLCL antibody
      • PLCL1 antibody
      • PLCL1_HUMAN antibody
      • PLDL1 antibody
      • PRIP antibody
      see all

    Anti-PLCL1 antibody images

    • Anti-PLCL1 antibody (ab93425) at 1/100 dilution + Jurkat cell line lysates at 35 µg

      Predicted band size : 123 kDa

    References for Anti-PLCL1 antibody (ab93425)

    ab93425 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab93425.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"