Overview

  • Product nameAnti-PLEKHA1 antibody
    See all PLEKHA1 primary antibodies
  • Description
    Rabbit polyclonal to PLEKHA1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Full length Human protein (NP_001001974.1)

  • Positive control
    • PLEKHA1 transfected 293T cell lysate, Mouse kidney tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab103821 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 46 kDa.

Target

  • FunctionBinds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane.
  • Tissue specificityHighly expressed in skeletal muscle, thymus, pancreas, placenta and lung. Detected at low levels in brain, heart, peripheral blood leukocytes, testis, ovary, spinal cord, thyroid, kidney, liver, small intestine and colon.
  • Sequence similaritiesContains 2 PH domains.
  • DomainBinds to membranes enriched in PtdIns3,4P2 via the C-terminal PH domain.
  • Cellular localizationCytoplasm. Cell membrane. Nucleus. Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2.
  • Information by UniProt
  • Database links
  • Alternative names
    • OTTHUMP00000020651 antibody
    • PH domain containing family A member 1 antibody
    • PH domain-containing family A member 1 antibody
    • PKHA1_HUMAN antibody
    • Pleckstrin homology domain containing family A member 1 antibody
    • Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member antibody
    • Pleckstrin homology domain-containing family A member 1 antibody
    • PLEKHA1 antibody
    • Tandem PH domain containing protein 1 antibody
    • Tandem PH domain-containing protein 1 antibody
    • TAPP 1 antibody
    • TAPP-1 antibody
    • TAPP1 antibody
    see all

Anti-PLEKHA1 antibody images

  • Anti-PLEKHA1 antibody (ab103821) at 1 µg/ml + Mouse kidney tissue lysate at 50 µg

    Predicted band size : 46 kDa
  • All lanes : Anti-PLEKHA1 antibody (ab103821) at 1 µg/ml

    Lane 1 : PLEKHA1 transfected 293T cell line lysate.
    Lane 2 : Non transfected 293T cell line lysate.

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 46 kDa

References for Anti-PLEKHA1 antibody (ab103821)

ab103821 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"