Overview

  • Product name(±)-Chlorpheniramine maleate
  • Description
    Potent H1 antagonist and SNRI
  • Biological descriptionPotent H1 antagonist (Ki = 2 nM) and serotonin-norepinephrine reuptake inhibitor (SNRI). Shows antiallergic, antidepressant and antianxiolytic activity.
  • Purity> 99%

Properties

    References for (±)-Chlorpheniramine maleate (ab120729)

    This product has been referenced in:
    • Miyata S  et al. Chlorpheniramine exerts anxiolytic-like effects and activates prefrontal 5-HT systems in mice. Psychopharmacology (Berl) 213:441-52 (2011). Read more (PubMed: 19823805) »
    • Rojas-Zamorano JA  et al. The H1 histamine receptor blocker, chlorpheniramine, completely prevents the increase in REM sleep induced by immobilization stress in rats. Pharmacol Biochem Behav 91:291-4 (2009). Read more (PubMed: 18700151) »
    • Aslanian R  et al. Identification of a dual histamine H1/H3 receptor ligand based on the H1 antagonist chlorpheniramine. Bioorg Med Chem Lett 13:1959-61 (2003). Read more (PubMed: 12781173) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"