Overview

  • Product nameAnti-PMCA1 antibody
    See all PMCA1 primary antibodies
  • Description
    Mouse monoclonal to PMCA1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment: MGDMANNSVA YSGVKNSLKE ANHDGDFGIT LAELRALMEL RSTDALRKIQ ESYGDVYGIC TKLKTSPNEG LSGNPADLER REAVFGKNFI PPKKPKT, corresponding to amino acids 1-98 of Human Calcium Pump PMCA1 ATPase

Properties

Applications

Our Abpromise guarantee covers the use of ab54878 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionThis magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.
    • Tissue specificityIsoform B is ubiquitously expressed. Isoform C is found in brain cortex, skeletal muscle and heart muscle. Isoform D has only been found in fetal skeletal muscle. Isoform K has been found in small intestine and liver.
    • Sequence similaritiesBelongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
    • DomainThe calmodulin-binding subdomain B is different in the different splice variants and shows pH dependent calmodulin binding properties in isoforms A, C, D and E.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • AT2B1_HUMAN antibody
      • ATP2B1 antibody
      • ATPase Ca++ transporting plasma membrane 1 antibody
      • Plasma membrane calcium ATPase 1 antibody
      • Plasma membrane calcium ATPase isoform 1 antibody
      • Plasma membrane calcium pump isoform 1 antibody
      • Plasma membrane calcium transporting ATPase 1 antibody
      • Plasma membrane calcium-transporting ATPase 1 antibody
      • PMCA 1 antibody
      • PMCA1 antibody
      see all

    Anti-PMCA1 antibody images

    • Western blot against tagged recombinant protein immunogen using ab54878 Calcium Pump PMCA1 ATPase antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    References for Anti-PMCA1 antibody (ab54878)

    ab54878 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"