Overview

  • Product name
  • Description
    Mouse polyclonal to PNPLA3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length PNPLA3 protein (Human) (AAH65195.1)

  • Positive control
    • PNPLA3 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab69170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 53 kDa (predicted molecular weight: 53 kDa).

Target

  • Relevance
    PNPLA3 is a multifunctional enzyme which has both triacylglycerol lipase and acylglycerol O-acyltransferase activities. It contains one patatin domain.
  • Cellular localization
    Membrane; Single pass type II membrane protein
  • Database links
  • Alternative names
    • Acylglycerol O acyltransferase antibody
    • Adiponutrin antibody
    • ADPN antibody
    • C22orf20 antibody
    • Calcium independent phospholipase A2 epsilon antibody
    • DJ796I17.1 antibody
    • iPLA(2)epsilon antibody
    • IPLA2-epsilon antibody
    • Patatin like phospholipase domain containing 3 antibody
    • patatin like phospholipase domain containing protein 3 antibody
    • phospholipase A2, calcium independent, epsilon antibody
    see all

Images

  • All lanes : Anti-PNPLA3 antibody (ab69170) at 1/500 dilution

    Lane 1 : PNPLA3 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 53 kDa
    Observed band size : 53 kDa

References

This product has been referenced in:
  • Ren T  et al. The Combination of Blueberry Juice and Probiotics Ameliorate Non-Alcoholic Steatohepatitis (NASH) by Affecting SREBP-1c/PNPLA-3 Pathway via PPAR-a. Nutrients 9:N/A (2017). Read more (PubMed: 28264426) »
  • Perttilä J  et al. PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis. Am J Physiol Endocrinol Metab 302:E1063-9 (2012). Read more (PubMed: 22338072) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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