Overview

  • Product name
  • Description
    Rabbit polyclonal to PNPLA8
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment corresponding to amino acids 129-358 of Human PNPLA8 (BC032999).

  • Positive control
    • A549 lysate, Human fetal liver

Properties

Applications

Our Abpromise guarantee covers the use of ab140151 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Predicted molecular weight: 88 kDa.
IHC-P 1/100 - 1/500.

Target

  • Function
    Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids.
  • Tissue specificity
    Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart.
  • Sequence similarities
    Contains 1 patatin domain.
  • Cellular localization
    Endoplasmic reticulum membrane. Golgi apparatus membrane. Cytoplasm > perinuclear region.
  • Information by UniProt
  • Database links
  • Alternative names
    • Calcium-independent phospholipase A2-gamma antibody
    • Intracellular membrane associated calcium independent phospholipase A2 gamma antibody
    • Intracellular membrane-associated calcium-independent phospholipase A2 gamma antibody
    • IPLA2 2 antibody
    • iPLA2 gamma antibody
    • IPLA2(GAMMA) antibody
    • iPLA2-2 antibody
    • iPLA2-gamma antibody
    • IPLA22 antibody
    • IPLA2G antibody
    • Patatin like phospholipase domain containing protein 8 antibody
    • Patatin-like phospholipase domain-containing protein 8 antibody
    • PLPL8_HUMAN antibody
    • PNPLA-gamma antibody
    • PNPLA8 antibody
    see all

Images

  • Anti-PNPLA8 antibody (ab140151) at 1/1000 dilution + A549 cell lysate

    Predicted band size : 88 kDa
  • Immunohistochemical analysis of formalin-fixed paraffin embedded Human fetal liver tissue labelling PNPLA8 with ab140151 at a 1/100 dilution.

References

ab140151 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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