Overview

  • Product nameAnti-PNPO antibody
    See all PNPO primary antibodies
  • Description
    Rabbit polyclonal to PNPO
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide designed between amino acids 232~261 from the C-terminal region of Human PNPO.

  • Positive control
    • 293 cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab102824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 30 kDa.

Target

  • FunctionCatalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
  • PathwayCofactor biosynthesis; B6 vitamer interconversion; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.
    Cofactor biosynthesis; B6 vitamer interconversion; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.
  • Involvement in diseaseDefects in PNPO are the cause of pyridoxine-5'-phosphate oxidase deficiency (PNPO deficiency) [MIM:610090]; also known as PNPO-related neonatal epileptic encephalopathy. The main feature of neonatal epileptic encephalopathy is the onset within hours of birth of a severe seizure disorder that does not respond to anticonvulsant drugs and can be fatal. Seizures can cease with the administration of PLP, being resistant to treatment with pyridoxine.
  • Sequence similaritiesBelongs to the pyridoxamine 5'-phosphate oxidase family.
  • Information by UniProt
  • Database links
  • Alternative names
    • EC 1.4.3.5 antibody
    • FLJ10535 antibody
    • PDXPO antibody
    • PNPO antibody
    • PNPO_HUMAN antibody
    • Pyridoxal 5' phosphate synthase antibody
    • pyridoxamine 5' phosphate oxidase antibody
    • Pyridoxamine phosphate oxidase antibody
    • Pyridoxamine-phosphate oxidase antibody
    • pyridoxine 5' phosphate oxidase antibody
    • Pyridoxine-5'-phosphate oxidase antibody
    see all

Anti-PNPO antibody images

  • Anti-PNPO antibody (ab102824) at 1/100 dilution + 293 cell line lysate at 35 µg

    Predicted band size : 30 kDa

References for Anti-PNPO antibody (ab102824)

ab102824 has not yet been referenced specifically in any publications.

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