Overview

  • Product name
    Anti-Poliovirus type 3 antibody [300-06]
    See all Poliovirus type 3 primary antibodies
  • Description
    Mouse monoclonal [300-06] to Poliovirus type 3
  • Specificity
    Reacts with Polio Virus type 3. There is no cross reactivity with type 1 and 2.
  • Tested applications
    Suitable for: ELISA, Sandwich ELISA, Neutralisingmore details
  • Species reactivity
    Reacts with Polio Virus type 3. Not yet tested in other species.
  • Immunogen

    Polio virus type 3 (inactivated)

  • Epitope
    Overlapping with that of ab47821.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Monoclonal
  • Clone number
    300-06
  • Myeloma
    x63-Ag8.653
  • Isotype
    IgG2a
  • Light chain type
    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab47803 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
Sandwich ELISA Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [45D5] to Poliovirus type 3 (ab47821). Ab47803 is recommended as capture antibody and recommended pair as detection antibody.
Neutralising Use at an assay dependent dilution. Use in combination with ab47821 to neutralize concentrated virus for at least 12 days.

Target

  • Relevance
    Poliovirus, the causative agent of poliomyelitis, was first isolated nearly 100 years ago. It may infect the nervous system and cause lasting paralysis. Poliovirus is a single stranded RNA virus and a member of the Picornavirus family. It has three strains: Poliovirus 1, 2 and 3. Replication of poliovirus RNA is accomplished by the error-prone viral RNA-dependent RNA polymerase. The cell receptor for poliovirus is CD155.

References

This product has been referenced in:
  • Asati A  et al. Fluorescence Adherence Inhibition Assay: A Novel Functional Assessment of Blocking Virus Attachment by Vaccine-Induced Antibodies. PLoS One 11:e0144261 (2016). Read more (PubMed: 26863313) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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