The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Detects a band of approximately 120 kDa (predicted molecular weight: 112 kDa).
RelevancePolo-like kinase (PLK) plays an important role in cell cycle regulation. It is required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Recent work led to the identification of a polo-like kinase kinase (PLKK) that is thought to be responsible for activation of PLK. Recent work (Erikson, et al., 2004) has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK.
Polo like kinase kinase 1 antibody
Serine/threonine kinase 10 antibody
stk10 a antibody
References for Anti-Polo like kinase kinase (phospho S482 + S486 + S490) antibody (ab30565)
has not yet been referenced specifically in any publications.
Publishing research using ab30565? Please let us know so that we can cite the reference in this datasheet.
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