Overview

  • Product nameAnti-POLR1C antibody
    See all POLR1C primary antibodies
  • Description
    Mouse monoclonal to POLR1C
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-347 of Human POLR1C

Properties

Applications

Our Abpromise guarantee covers the use of ab56744 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
    • Involvement in diseaseTreacher Collins syndrome 3 (TCS3) [MIM:248390]: A form of Treacher Collins syndrome, a disorder of craniofacial development. Treacher Collins syndrome is characterized by a combination of bilateral downward slanting of the palpebral fissures, colobomas of the lower eyelids with a paucity of eyelashes medial to the defect, hypoplasia of the facial bones, cleft palate, malformation of the external ears, atresia of the external auditory canals, and bilateral conductive hearing loss. Note=The disease is caused by mutations affecting the gene represented in this entry.
    • Sequence similaritiesBelongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • 40kDa antibody
      • AA409007 antibody
      • AA959927 antibody
      • Ac2-127 antibody
      • AC40 antibody
      • AL024089 antibody
      • DNA directed RNA polymerase I subunit C antibody
      • DNA directed RNA polymerases I and III 40 kDa polypeptide antibody
      • DNA directed RNA polymerases I and III subunit RPAC1 antibody
      • DNA-directed RNA polymerase I subunit C antibody
      • DNA-directed RNA polymerases I and III 40 kDa polypeptide antibody
      • DNA-directed RNA polymerases I and III subunit RPAC1 antibody
      • MGC105583 antibody
      • MGC161175 antibody
      • POLR1C antibody
      • POLR1E antibody
      • Polymerase (RNA) I polypeptide C, 30kDa antibody
      • RNA polymerase 1 1 antibody
      • RNA polymerases I and III subunit AC1 antibody
      • RP3-337H4.4 antibody
      • RPA39 antibody
      • RPA40 antibody
      • RPA5 antibody
      • RPAC1 antibody
      • RPAC1_HUMAN antibody
      • RPC40 antibody
      • Rpo1 1 antibody
      • TCS3 antibody
      see all

    Anti-POLR1C antibody images

    • POLR1C antibody (ab56744) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human thyroid nodular goiter.


    • Predicted band size : 39 kDa
      POLR1C antibody (ab56744) at 1ug/lane + K-562 cell lysate at 25ug/lane.

    References for Anti-POLR1C antibody (ab56744)

    ab56744 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab56744.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"