Anti-POLR1C antibody - C-terminal (ab82861)


  • Product name
    Anti-POLR1C antibody - C-terminal
    See all POLR1C primary antibodies
  • Description
    Rabbit polyclonal to POLR1C - C-terminal
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide selected from the C terminal region of human POLR1C conjugated to KLH (NP_976035).

  • Positive control
    • A2058 cell line lysates.



Our Abpromise guarantee covers the use of ab82861 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).
ELISA 1/1000.


  • Function
    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
  • Involvement in disease
    Treacher Collins syndrome 3 (TCS3) [MIM:248390]: A form of Treacher Collins syndrome, a disorder of craniofacial development. Treacher Collins syndrome is characterized by a combination of bilateral downward slanting of the palpebral fissures, colobomas of the lower eyelids with a paucity of eyelashes medial to the defect, hypoplasia of the facial bones, cleft palate, malformation of the external ears, atresia of the external auditory canals, and bilateral conductive hearing loss. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Sequence similarities
    Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • 40kDa antibody
    • AA409007 antibody
    • AA959927 antibody
    • Ac2-127 antibody
    • AC40 antibody
    • AL024089 antibody
    • DNA directed RNA polymerase I subunit C antibody
    • DNA directed RNA polymerases I and III 40 kDa polypeptide antibody
    • DNA directed RNA polymerases I and III subunit RPAC1 antibody
    • DNA-directed RNA polymerase I subunit C antibody
    • DNA-directed RNA polymerases I and III 40 kDa polypeptide antibody
    • DNA-directed RNA polymerases I and III subunit RPAC1 antibody
    • MGC105583 antibody
    • MGC161175 antibody
    • POLR1C antibody
    • POLR1E antibody
    • Polymerase (RNA) I polypeptide C, 30kDa antibody
    • RNA polymerase 1 1 antibody
    • RNA polymerase I subunit C antibody
    • RNA polymerases I and III subunit AC1 antibody
    • RP3-337H4.4 antibody
    • RPA39 antibody
    • RPA40 antibody
    • RPA5 antibody
    • RPAC1 antibody
    • RPAC1_HUMAN antibody
    • RPC40 antibody
    • Rpo1 1 antibody
    • TCS3 antibody
    see all


  • Anti-POLR1C antibody - C-terminal (ab82861) at 1/50 dilution + A2058 cell line lysates at 35 µg

    Predicted band size : 39 kDa
    Observed band size : 39 kDa


ab82861 has not yet been referenced specifically in any publications.

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