1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
FunctionDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.
Involvement in diseaseTreacher Collins syndrome 2
Sequence similaritiesBelongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.